根據佛(fo)山(shan)市地區(qu)生產(chan)(chan)(chan)總值(zhi)(zhi)統一(yi)核(he)算，2021年高(gao)明(ming)區(qu)實現生產(chan)(chan)(chan)總值(zhi)(zhi)（初步核(he)算數）為977.10億元，按可比(bi)(bi)價(jia)格計算，同(tong)比(bi)(bi)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)7.0%。其中(zhong)：第(di)一(yi)產(chan)(chan)(chan)業(ye)(ye)增(zeng)(zeng)(zeng)加(jia)值(zhi)(zhi)32.41億元，增(zeng)(zeng)(zeng)長(chang)(chang)(chang)10.1%；第(di)二產(chan)(chan)(chan)業(ye)(ye)增(zeng)(zeng)(zeng)加(jia)值(zhi)(zhi)728.78億元，增(zeng)(zeng)(zeng)長(chang)(chang)(chang)6.3%；第(di)三(san)產(chan)(chan)(chan)業(ye)(ye)增(zeng)(zeng)(zeng)加(jia)值(zhi)(zhi)215.9億元，增(zeng)(zeng)(zeng)長(chang)(chang)(chang)9.0%。三(san)次產(chan)(chan)(chan)業(ye)(ye)結構比(bi)(bi)重(zhong)為3.3：74.6：22.1。在(zai)第(di)三(san)產(chan)(chan)(chan)業(ye)(ye)中(zhong)，批發(fa)和(he)零售(shou)業(ye)(ye)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)2.4%，交通運輸、倉儲和(he)郵政業(ye)(ye)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)70.4%，住宿(su)和(he)餐飲(yin)業(ye)(ye)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)13.2%，金融業(ye)(ye)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)4.0%，房地產(chan)(chan)(chan)業(ye)(ye)下降4.9%，其他服務業(ye)(ye)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)10.0%。實現現代(dai)服務業(ye)(ye)增(zeng)(zeng)(zeng)加(jia)124.01億元，同(tong)比(bi)(bi)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)5.6%。按常住人口計算，全區(qu)人均地區(qu)生產(chan)(chan)(chan)總值(zhi)(zhi)達到207651元，同(tong)比(bi)(bi)增(zeng)(zeng)(zeng)長(chang)(chang)(chang)6.5%。

2021年(nian)(nian)(nian)高(gao)明區糧食(shi)作物(wu)播種(zhong)面(mian)積10.01萬(wan)畝(mu)，同(tong)比下(xia)(xia)降(jiang)(jiang)6.9%。全(quan)(quan)(quan)年(nian)(nian)(nian)糧食(shi)產(chan)量3.53萬(wan)噸(dun)，下(xia)(xia)降(jiang)(jiang)5.9%。全(quan)(quan)(quan)年(nian)(nian)(nian)全(quan)(quan)(quan)部(bu)工業增(zeng)加值比上(shang)年(nian)(nian)(nian)增(zeng)長(chang)5.0%。全(quan)(quan)(quan)年(nian)(nian)(nian)資質等(deng)級(ji)以上(shang)建筑業企業31家，完(wan)成(cheng)建筑業總產(chan)值18.60億元，同(tong)比增(zeng)長(chang)36.6%。全(quan)(quan)(quan)年(nian)(nian)(nian)固(gu)定(ding)資產(chan)投資同(tong)比下(xia)(xia)降(jiang)(jiang)5.6%。全(quan)(quan)(quan)年(nian)(nian)(nian)實(shi)現(xian)社會消費品零售總額(e)130.72億元，同(tong)比增(zeng)長(chang)5.2%。全(quan)(quan)(quan)年(nian)(nian)(nian)實(shi)現(xian)進出口總額(e)269.80億元，同(tong)比增(zeng)長(chang)24.4%。全(quan)(quan)(quan)年(nian)(nian)(nian)接待游客990.5萬(wan)人次，同(tong)比增(zeng)長(chang)47.1%；實(shi)現(xian)旅游總收入42.3億元，同(tong)比增(zeng)長(chang)47.0%。