蜂(feng)膠的消炎鎮痛(tong)作用

蜂膠(jiao)(jiao)是(shi)很(hen)好的(de)(de)(de)消(xiao)炎(yan)(yan)(yan)鎮(zhen)痛劑，用(yong)(yong)(yong)(yong)(yong)蜂膠(jiao)(jiao)提取液(ye)治療(liao)大白鼠關節(jie)炎(yan)(yan)(yan)的(de)(de)(de)實驗(yan)(yan)證明蜂膠(jiao)(jiao)有抗炎(yan)(yan)(yan)作(zuo)用(yong)(yong)(yong)(yong)(yong)；用(yong)(yong)(yong)(yong)(yong)甲醇誘導小(xiao)鼠關節(jie)炎(yan)(yan)(yan)和(he)(he)水(shui)(shui)腫(zhong)，然后用(yong)(yong)(yong)(yong)(yong)蜂膠(jiao)(jiao)進(jin)行試(shi)(shi)驗(yan)(yan)，證明蜂膠(jiao)(jiao)對(dui)這兩種炎(yan)(yan)(yan)癥(zheng)均有抗炎(yan)(yan)(yan)效果，用(yong)(yong)(yong)(yong)(yong)蜂膠(jiao)(jiao)和(he)(he)阿(a)司(si)匹林(0. 2g/kg)對(dui)照，給大鼠口服受(shou)藥后1小(xiao)時，將(jiang)其(qi)后肢(zhi)進(jin)行人工(gong)誘發(fa)炎(yan)(yan)(yan)癥(zheng)性水(shui)(shui)腫(zhong)，然后每小(xiao)時測定其(qi)炎(yan)(yan)(yan)癥(zheng)腫(zhong)脹的(de)(de)(de)程(cheng)度，試(shi)(shi)驗(yan)(yan)證明，蜂膠(jiao)(jiao)和(he)(he)阿(a)司(si)匹林對(dui)炎(yan)(yan)(yan)癥(zheng)腫(zhong)脹都有抑制作(zuo)用(yong)(yong)(yong)(yong)(yong)，而且它們的(de)(de)(de)抗炎(yan)(yan)(yan)作(zuo)用(yong)(yong)(yong)(yong)(yong)十分相似(si)。用(yong)(yong)(yong)(yong)(yong)二甲苯涂抹小(xiao)鼠耳(er)部使鼠耳(er)腫(zhong)脹，試(shi)(shi)驗(yan)(yan)證明，蜂膠(jiao)(jiao)抗炎(yan)(yan)(yan)作(zuo)用(yong)(yong)(yong)(yong)(yong)比“消(xiao)炎(yan)(yan)(yan)痛”強。

蜂(feng)膠(jiao)有鎮(zhen)(zhen)痛(tong)作(zuo)用(yong)(yong)。沈勝利(li)等(1986)選擇雄(xiong)性(xing)小鼠(shu)(shu)采用(yong)(yong)電擊法，試驗結(jie)果證明(ming)，蜂(feng)膠(jiao)對電擊小鼠(shu)(shu)尾根部具有鎮(zhen)(zhen)痛(tong)作(zuo)用(yong)(yong)，并能(neng)維(wei)持一定時間。峰下(xia)哲(zhe)等(1992)采用(yong)(yong)給(gei)小鼠(shu)(shu)腹腔(qiang)注射0.7%乙酸，引起扭(niu)曲反(fan)應作(zuo)為指標，證明(ming)了蜂(feng)膠(jiao)經口飼喂能(neng)達到與消炎(yan)痛(tong)同等或更強的鎮(zhen)(zhen)痛(tong)效應。

蜂(feng)(feng)膠(jiao)有(you)很強的(de)(de)抗潰(kui)(kui)瘍(yang)(yang)作用(yong)。用(yong)五(wu)氧化二砷和咖啡(fei)因給大鼠(shu)造(zao)(zao)成(cheng)實(shi)驗(yan)性(xing)(xing)(xing)胃潰(kui)(kui)瘍(yang)(yang)，試驗(yan)證(zheng)明，給蜂(feng)(feng)膠(jiao)浸液和甲(jia)基尿嘧啶的(de)(de)治療組(zu)，其大白鼠(shu)潰(kui)(kui)瘍(yang)(yang)愈合(he)平均面(mian)(mian)積相(xiang)似，均比對(dui)照(zhao)組(zu)(給水)的(de)(de)潰(kui)(kui)瘍(yang)(yang)平均愈合(he)而積小(xiao)(xiao)得(de)多，表現(xian)為(wei)中毒癥狀輕(qing)，體重(zhong)增加，而對(dui)照(zhao)組(zu)卻呈現(xian)亞急性(xing)(xing)(xing)砷中毒;用(yong)粒狀氫氧化鈉將金(jin)黃地(di)鼠(shu)背前部致為(wei)實(shi)驗(yan)性(xing)(xing)(xing)潰(kui)(kui)瘍(yang)(yang)，用(yong)蜂(feng)(feng)膠(jiao)酊(ding)涂抹(mo)潰(kui)(kui)瘍(yang)(yang)處，與不(bu)涂藥(yao)處對(dui)照(zhao)，其結果證(zheng)明，蜂(feng)(feng)膠(jiao)酊(ding)能促進(jin)潰(kui)(kui)瘍(yang)(yang)愈合(he)，縮短病程1/2一1/3。從病理學鏡檢觀察，蜂(feng)(feng)膠(jiao)確有(you)消炎，促進(jin)組(zu)織(zhi)修復的(de)(de)功(gong)效(xiao)。用(yong)濃乙酸對(dui)雄(xiong)性(xing)(xing)(xing)大白鼠(shu)胃壁造(zao)(zao)成(cheng)潰(kui)(kui)瘍(yang)(yang)，實(shi)驗(yan)證(zheng)明，蜂(feng)(feng)膠(jiao)有(you)愈合(he)作用(yong)，不(bu)僅潰(kui)(kui)瘍(yang)(yang)愈合(he)率明顯高于對(dui)照(zhao)組(zu)，而且潰(kui)(kui)瘍(yang)(yang)面(mian)(mian)積縮小(xiao)(xiao)和病理組(zu)織(zhi)學改變亦有(you)明顯差(cha)別。